Hsv 2 Igg Positive Range
Hello i just got test results back for hsv 2 it says positive for the results but the reference range negative what does that mean answered by dr.
Hsv 2 igg positive range. Clinical manifestations include genital tract infections neonatal herpes meningoencephalitis keratoconjunctivitis and gingivostomatitis. Herpes simplex virus hsv types 1 and 2 are members of the herpesviridae family and produce infections that may range from mild stomatitis to disseminated and fatal disease. Hsv 2 igg 5 high positive meaning long term infection. The chances of false positive results increase as the likelihood of the infection decreases in the person being tested.
Most hsv serology assays however are not type specific. The herpeselect igg assays distinguish between hsv 1 and hsv 2 on the basis of differences in the patient s immune response to hsv glycoprotein g gg. The herpes igg test aims to identify whether you have been exposed to the hsv 1 the type primarily associated with cold sores or hsv 2 the type that mainly causes genital herpes. With that being said hsv 1 can cause a genital infection and hsv 2 can cause oral infection usually as a result of oral sex.
Clinical conditions associated with hsv infection include gingivostomatitis keratitis encephalitis vesicular skin eruptions aseptic meningitis neonatal herpes genital tract infections and disseminated primary. Or is it possible that even with a 5 igg it is a recent infection. For instance asha says that while an igg test can distinguish between hsv 1 and hsv 2 the problem is that the time it takes for igg antibodies to reach a detectable level varies from person to. Because igg antibodies to hsv persist for life serologic assays can detect infection even in the absence of lesions.
Is it safe to assume that with an hsv 2 igg of 5 i have had this virus for a very long time. Means that the normal should be negative. In a patient with no history of lesion disease a positive result for this test may be indicative that the primary infection was asymptomatic. Per cdc guidelines specimens with equivocal or low positive results for hsv 2 type specific igg will reflex for supplemental testing by another assay.
Herpes simplex virus 2 igg type specific antibody herpes simplex virus hsv is responsible for several clinically significant human viral diseases with severity ranging from inapparent to fatal.